Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484198 | 0.77 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL5738210 | 0.77 | ADORA2A (0.32) | KCNN4 | |
| SCHEMBL3827052 | 0.77 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL5286108 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL8307156 | 0.73 | ABCG2 (0.36) | — | |
| SCHEMBL6411394 | 0.73 | NOTUM (0.34) | CDK2 | |
| SCHEMBL1828996 | 0.73 | KDM4E (0.39) | — | |
| SCHEMBL7802981 | 0.73 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL9670896 | 0.72 | — | — | |
| SCHEMBL6958918 | 0.70 | TDP1 (0.34) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828152-A2 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FACTOR VIIA | Bristol-Myers Squibb Company (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062972-A2 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FACTOR VIIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-15 | — | — | WO | disclosed |