Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161282 | 0.76 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL5240366 | 0.74 | KCNN4 (0.31) | — | |
| SCHEMBL3827052 | 0.74 | KCNN4 (0.33) | ALDH1A1TSHRHPGDHSD17B10KDM4E | |
| SCHEMBL5738210 | 0.74 | ADORA2A (0.32) | NPSR1 | |
| SCHEMBL1484198 | 0.74 | KCNN4 (0.31) | — | |
| SCHEMBL7838930 | 0.71 | CYP3A4 (0.36) | ALDH1A1LMNANPBWR1MAPTELANE | |
| SCHEMBL22541579 | 0.71 | HSP90AA1 (0.31) | — | |
| Water SCHEMBL7413277 | 0.70 | — | — | |
| SCHEMBL11159377 | 0.70 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL649565 | 0.70 | HPGD (0.56) | ALDH1A1HPGDHSD17B10NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037800-A1 | Method of treating neurological disorders using clotrimazole and derivatives thereof | ENVIVO PHARMACEUTICALS, INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2007002497-A1 | METHOD OF TREATING NEUROLOGICAL DISORDERS USING CLOTRIMAZOLE AND DERIVATIVES THEREOF | ENVIVO PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037800-A1 | Method of treating neurological disorders using clotrimazole and derivatives thereof | HTT, HYPK, GRIK3 | ALDH1A1 2228/4885TSHR 906/4885HPGD 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.