Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602983 | 0.83 | LMNA (0.74) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL963949 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2LMNAALDH1A1NAMPTTSHR | |
| SCHEMBL30352411 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2LMNAALDH1A1NAMPTTSHR | |
| SCHEMBL2322638 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL10192028 | 0.81 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL3836378 | 0.81 | BCHE (0.64) | BCHEPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13995026 | 0.80 | SMN1; SMN2 (0.66) | BCHESMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL22550549 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL3042748 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL6810771 | 0.80 | SMN1; SMN2 (0.60) | POLBSMN1; SMN2LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773847-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010040-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-26 | — | — | WO | disclosed |