Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 12/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231224 | 0.88 | GSK3B (0.46) | PTAFRGSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL13986945 | 0.87 | GSK3B (0.58) | PTAFRGSK3BRECQLHDAC3HDAC4 | |
| SCHEMBL5231115 | 0.85 | GSK3B (0.46) | PTAFRGSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL5244050 | 0.78 | GSK3B (0.61) | PTAFRGSK3B | |
| SCHEMBL5231152 | 0.76 | GSK3B (0.55) | GSK3BAPP | |
| SCHEMBL5230846 | 0.76 | GSK3B (0.76) | PTAFRGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL13986937 | 0.75 | GSK3B (0.61) | PTAFRGSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL5232027 | 0.74 | EPHX1 (0.51) | GSK3BRECQL | |
| SCHEMBL5243802 | 0.74 | GSK3B (0.55) | PTAFRGSK3B | |
| SCHEMBL13987013 | 0.72 | GSK3B (0.62) | PTAFRGSK3BHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611121-B1 | PYRIDAZINONE DERIVATIVES AS CDK2-INHIBITORS | AVENTIS PHARMA SA (FR) | 2007-08-08 | — | — | EP | claimed |