Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.72 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244391 | 0.93 | GNAI3 (0.62) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL25504367 | 0.91 | GNAI3 (0.60) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL8972980 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL8972813 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL1045855 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL768398 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL4450061 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL7060548 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL8972823 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL18203194 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778652-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | EntreMed, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006023844-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED, INC. (US) | 2006-03-02 | — | — | WO | disclosed |