Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203308 | 0.94 | ALDH1A1 (0.65) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL29434423 | 0.94 | ALDH1A1 (0.65) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL16785484 | 0.94 | ALDH1A1 (0.65) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL18515737 | 0.94 | ALDH1A1 (0.65) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL4865330 | 0.90 | ALDH1A1 (0.57) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL5398966 | 0.89 | ALDH1A1 (0.60) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL4908931 | 0.89 | ALDH1A1 (0.56) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL5399073 | 0.89 | ALDH1A1 (0.60) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL5401473 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP2C19LMNAKMT2ACYP3A4 | |
| SCHEMBL5244764 | 0.88 | ALDH1A1 (0.58) | ALDH1A1CYP2C19LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947492-A | Process for producing β-phenyl-γ-amino butyric acid hydrochloride | PEREKALIN VSEVOLOD VASILIEVICH | 1976-03-30 | — | — | US | claimed |
| US-7312335-B2 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1758899-A1 | ASYMMETRIC MICHAEL AND ALDOL ADDITION USING BIFUNCTIONAL CINCHONA-ALKALOID-BASED CATALYSTS | Brandeis University (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20060014956-A1 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY | 2006-01-19 | — | — | US | disclosed |
| WO-2005121137-A1 | ASYMMETRIC MICHAEL AND ALDOL ADDITION USING BIFUNCTIONAL CINCHONA-ALKALOID-BASED CATALYSTS | BRANDEIS UNIVERSITY (US) | 2005-12-22 | — | — | WO | disclosed |
| US-3947492-A | Process for producing β-phenyl-γ-amino butyric acid hydrochloride | PEREKALIN VSEVOLOD VASILIEVICH | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014956-A1 | Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts | ALDH3A1, NQO1, DERA | ALDH1A1 13/4885CYP2C19 631/4885LMNA 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.