Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138360 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL5646015 | 0.78 | LIPE (0.61) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL29817180 | 0.75 | LMNA (0.70) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL3137922 | 0.74 | MEN1 (0.54) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL3143585 | 0.74 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL8925732 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL3137365 | 0.73 | PRKAA2 (0.56) | HIF1AALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL3143560 | 0.72 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A | |
| SCHEMBL12276572 | 0.72 | NPC1 (0.47) | LMNASMN1; SMN2HIF1AALDH1A1USP2 | |
| SCHEMBL3143051 | 0.72 | MEN1 (0.51) | LMNASMN1; SMN2CYP3A4CYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |