Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244319 | 0.96 | MEN1 (0.36) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5249178 | 0.92 | SMPD1 (0.34) | HPGDALDH1A1KDM4EACKR3 | |
| SCHEMBL3116642 | 0.91 | TP53 (0.40) | KMT2AMEN1HPGDSMN1; SMN2LMNA | |
| SCHEMBL5244268 | 0.91 | PDK2 (0.35) | ACKR3 | |
| SCHEMBL5247607 | 0.91 | KMT2A (0.43) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3111906 | 0.91 | SMPD1 (0.38) | ACKR3 | |
| SCHEMBL5247629 | 0.91 | DGAT1 (0.34) | KMT2AACKR3TP53 | |
| SCHEMBL5247451 | 0.90 | SMPD1 (0.34) | SMN1; SMN2MAPTACKR3TP53 | |
| SCHEMBL5250028 | 0.90 | SMPD1 (0.33) | ACKR3TP53 | |
| SCHEMBL5244453 | 0.90 | KMT2A (0.41) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |