Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527539 | 1.00 | DPP7 (0.34) | DPP7EPHX2GNAI3GNAO1GNAI1 | |
| Trifluoroacetic Acid SCHEMBL8920265 | 0.92 | S1PR1 (0.37) | EPHX2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8921719 | 0.92 | S1PR1 (0.37) | EPHX2ALDH1A1 | |
| SCHEMBL526030 | 0.91 | HDAC3 (0.33) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8778900 | 0.91 | HDAC3 (0.33) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8779144 | 0.91 | HDAC3 (0.33) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL528796 | 0.88 | RRM1 (0.35) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8778928 | 0.88 | RRM1 (0.35) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL526843 | 0.87 | RRM1 (0.35) | DPP7GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8778929 | 0.87 | RRM1 (0.35) | DPP7GNAI3GNAO1GNAI1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190278-A1 | Compounds for the Treatment/Prevention of Ocular Inflammatory Diseases | LABORATOIRES FOURNIER SA (FR) | 2013-07-25 | — | — | US | disclosed |
| EP-2598131-A1 | COMPOUNDS FOR THE TREATMENT/PREVENTION OF OCULAR INFLAMMATORY DISEASES | Laboratoires Fournier S.A. (FR) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013884-A1 | COMPOUNDS FOR THE TREATMENT/PREVENTION OF OCULAR INFLAMMATORY DISEASES | LABORATOIRES FOURNIER SA (FR) | 2012-02-02 | — | — | WO | disclosed |
| EP-0669316-B1 | Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER IND & SANTE (FR) | 1997-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190278-A1 | Compounds for the Treatment/Prevention of Ocular Inflammatory Diseases | TNF, NFKBIA, ALDH1A2 | DPP7 292/4885EPHX2 1852/4885GNAI3 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.