Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246381 | 0.89 | PARP1 (0.34) | PARP1IRAK4 | |
| SCHEMBL5248275 | 0.87 | PARP1 (0.33) | PARP1 | |
| SCHEMBL5244562 | 0.86 | PARP1 (0.33) | PARP1IRAK4 | |
| SCHEMBL3749075 | 0.79 | PARP1 (0.34) | PARP1IRAK4 | |
| SCHEMBL3750058 | 0.75 | PARP14 (0.34) | PARP1 | |
| SCHEMBL3752317 | 0.69 | HTR2C (0.39) | — | |
| SCHEMBL3744443 | 0.69 | THRB (0.35) | PARP1IRAK4 | |
| SCHEMBL3756206 | 0.67 | PARP1 (0.36) | PARP1IRAK4 | |
| SCHEMBL3750551 | 0.67 | PARP1 (0.34) | PARP1 | |
| SCHEMBL3750053 | 0.67 | PARP1 (0.35) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006066173-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1828177-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066173-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |