Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4830313 | 0.99 | MMP8 (0.46) | MMP8BACE1ALDH1A1LMNAMEN1 | |
| SCHEMBL5246174 | 0.94 | MMP8 (0.53) | MMP8ALDH1A1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL4834764 | 0.93 | MMP8 (0.52) | MMP8ALDH1A1MEN1KMT2AATM | |
| SCHEMBL5246557 | 0.88 | NPC1 (0.48) | MMP8ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5244674 | 0.88 | KMT2A (0.48) | MMP8ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5245143 | 0.88 | MMP8 (0.47) | MMP8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5248547 | 0.88 | SMN1; SMN2 (0.48) | MMP8ALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4830172 | 0.87 | KMT2A (0.47) | MMP8ALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4827301 | 0.87 | MMP8 (0.46) | MMP8ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4826419 | 0.87 | SMN1; SMN2 (0.47) | MMP8ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |
| EP-1707564-A2 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-10-04 | — | — | EP | disclosed |