Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RPS27 | P42677 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246284 | 0.92 | EPHX2 (0.49) | EPHX2RORCDRD2MAPK8MAPK9 | |
| SCHEMBL5244275 | 0.89 | MAPK8 (0.47) | EPHX2RORCDRD2MAPK8MAPK9 | |
| SCHEMBL5245729 | 0.86 | SMPD1 (0.40) | — | |
| SCHEMBL5247632 | 0.85 | GLS (0.42) | MIF | |
| SCHEMBL3112251 | 0.84 | EPHX2 (0.36) | EPHX2NR1H4MIF | |
| SCHEMBL5247900 | 0.84 | SMPD1 (0.44) | DRD2 | |
| SCHEMBL5244569 | 0.83 | SMPD1 (0.41) | — | |
| SCHEMBL5247618 | 0.83 | SMPD1 (0.43) | DRD2 | |
| SCHEMBL5248314 | 0.83 | SMPD1 (0.39) | — | |
| SCHEMBL5247392 | 0.83 | GLS (0.47) | DRD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |