Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247026 | 0.92 | EBP (0.62) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL5244816 | 0.84 | EBP (0.58) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL3746702 | 0.83 | SIGMAR1 (0.42) | EBPSIGMAR1CXCR3KDM4ENPC1 | |
| SCHEMBL3741896 | 0.79 | RAB9A (0.49) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL9774919 | 0.78 | SMN1; SMN2 (0.53) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL10376284 | 0.78 | EBP (0.89) | EBPSIGMAR1CXCR3NPC1RAB9A | |
| SCHEMBL10377126 | 0.78 | EBP (0.55) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL10377125 | 0.78 | EBP (0.55) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL9774901 | 0.76 | EBP (0.61) | EBPSIGMAR1CXCR3LMNAMAPK1 | |
| SCHEMBL10375146 | 0.76 | EBP (0.78) | EBPSIGMAR1NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066173-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |