Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107164 | 0.86 | MEN1 (0.40) | RAB9AMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5250048 | 0.85 | EPHX2 (0.46) | RAB9AMEN1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL5247519 | 0.85 | CCR1 (0.40) | MEN1KMT2AKDM4EMAPTGABRA5 | |
| SCHEMBL5247642 | 0.84 | CCR1 (0.41) | NPC1RAB9AMEN1KMT2AGABRA5 | |
| SCHEMBL3111992 | 0.84 | SPHK2 (0.45) | NPC1RAB9AMEN1KMT2AGABRA5 | |
| SCHEMBL5246363 | 0.83 | KDM4E (0.33) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5244539 | 0.83 | SMO (0.44) | MEN1KMT2AMAPTSMN1; SMN2EPHX2 | |
| SCHEMBL5246369 | 0.83 | KDM4E (0.32) | MEN1KMT2AKDM4EMAPTGABRA5 | |
| SCHEMBL5249136 | 0.83 | CACNA1G (0.40) | MEN1KMT2AMAPTEPHX2CCR1 | |
| SCHEMBL5247431 | 0.83 | RIPK1 (0.44) | MEN1KMT2ASMN1; SMN2EPHX2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |