Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | LOX | P28300 | 2/20 | 0.65 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738321 | 0.92 | MAPK14 (0.76) | HPGDHTTKMT2AHDAC8HDAC2 | |
| SCHEMBL257930 | 0.90 | HPGD (0.63) | HPGDHTTKMT2AHDAC8HDAC2 | |
| SCHEMBL4035947 | 0.87 | RAB9A (0.65) | HPGDKMT2AHDAC8HDAC6MAPK14 | |
| SCHEMBL2922655 | 0.87 | MMP13 (0.81) | HPGDHTTKMT2AHDAC8HDAC2 | |
| SCHEMBL8738317 | 0.86 | HPGD (0.97) | HPGDHTTHDAC8HDAC2HDAC6 | |
| SCHEMBL5709300 | 0.86 | HPGD (0.84) | HPGDHTTHDAC6SMN1; SMN2MAPK14 | |
| SCHEMBL11900328 | 0.85 | HDAC6 (0.87) | HPGDHTTKMT2AHDAC8HDAC2 | |
| SCHEMBL177585 | 0.85 | HTT (0.63) | HPGDHTTKMT2AHDAC8HDAC2 | |
| SCHEMBL8782975 | 0.84 | HDAC8 (0.69) | KMT2AHDAC8SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27781796 | 0.84 | HDAC2 (0.65) | HPGDHTTKMT2AHDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |