Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252171 | 0.79 | CCR8 (0.46) | MTNR1BMTNR1AHTR1ACCR8 | |
| SCHEMBL3252168 | 0.79 | CCR8 (0.46) | MTNR1BMTNR1AHTR1ACCR8 | |
| SCHEMBL3239669 | 0.76 | CCR8 (0.46) | MTNR1BMTNR1AHTR1ACCR8 | |
| SCHEMBL3239661 | 0.76 | CCR8 (0.46) | MTNR1BMTNR1AHTR1ACCR8 | |
| SCHEMBL3246012 | 0.75 | CCR8 (0.44) | MTNR1BMTNR1AHTR1ACCR8 | |
| SCHEMBL3243038 | 0.72 | MTNR1B (0.51) | MTNR1BMTNR1A | |
| SCHEMBL3246023 | 0.70 | MTNR1B (0.55) | MTNR1BMTNR1A | |
| SCHEMBL3248037 | 0.68 | MTNR1B (0.50) | MTNR1BMTNR1AMAPT | |
| SCHEMBL3249271 | 0.68 | MTNR1B (0.49) | MTNR1BMTNR1AMAPT | |
| SCHEMBL3252874 | 0.68 | KCNH2 (0.59) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799674-A1 | NEW PIPERIDINE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038172-A1 | NEW PIPERIDINE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-04-13 | — | — | WO | disclosed |