Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245809 | 0.75 | GPR84 (0.33) | ATMRAB9ASMN1; SMN2 | |
| SCHEMBL3840526 | 0.75 | HSD17B10 (0.38) | KDM4EALDH1A1HTTHSD17B10CYP1A2 | |
| SCHEMBL3842031 | 0.72 | CYP1A2 (0.36) | ALDH1A1HSD17B10CYP1A2KMT2A | |
| SCHEMBL16730912 | 0.67 | GPR84 (0.56) | ATMCYP1A2NPC1 | |
| SCHEMBL18805430 | 0.65 | CYP2A6 (0.46) | MAPTKDM4EATMALDH1A1GAA | |
| SCHEMBL4419977 | 0.65 | ATM (0.34) | ATM | |
| SCHEMBL4418345 | 0.64 | ATM (0.48) | MAPTKDM4EATMALDH1A1MEN1 | |
| SCHEMBL2030771 | 0.64 | GPR84 (0.43) | ATMALDH1A1GAAPOLB | |
| SCHEMBL15359202 | 0.62 | CYP2A6 (0.35) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL15716703 | 0.62 | PARP1 (0.40) | KDM4EALDH1A1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833830-A1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006066955-A1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-06-29 | — | — | WO | disclosed |