Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840990 | 0.78 | CYP1A2 (0.54) | SMN1; SMN2 | |
| SCHEMBL5665566 | 0.76 | GABRA1 (0.54) | — | |
| SCHEMBL5246798 | 0.75 | MAPT (0.33) | ATMRAB9ASMN1; SMN2 | |
| SCHEMBL3842038 | 0.75 | GABRA1 (0.39) | SMN1; SMN2 | |
| SCHEMBL3840992 | 0.75 | HSD17B10 (0.35) | — | |
| SCHEMBL3840439 | 0.72 | CYP1A2 (0.36) | CYP2A6 | |
| SCHEMBL16730912 | 0.71 | GPR84 (0.56) | GPR84HTR2ACYP2A6ATM | |
| SCHEMBL5039480 | 0.68 | — | — | |
| SCHEMBL15730301 | 0.66 | PDE3B (0.37) | GPR84ATM | |
| SCHEMBL4418345 | 0.64 | ATM (0.48) | GPR84HTR2AHTR2CHTR2BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833830-A1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006066955-A1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-06-29 | — | — | WO | disclosed |