Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30122857 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL14958356 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| Hydrazine SCHEMBL14954414 | 0.95 | ALDH1A1 (0.62) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL21694048 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL2588646 | 0.88 | MAPT (0.55) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL16619850 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL96635 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL15961199 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| SCHEMBL14835707 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1TUBB1TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL23711567 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPK1TUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115463119-A | VEGFR-2 inhibitor and preparation and application thereof | 青岛科技大学 | 2022-12-13 | — | — | CN | claimed |
| CN-106278941-A | Nine kinds of PTP1B inhibitor and synthesis thereof and application | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | 2017-01-04 | — | — | CN | claimed |
| US-8816129-B2 | PTP1B inhibitors, synthesis thereof and application thereof in preparation of medicaments for treating type 2 diabetes mellitus | INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2014-08-26 | — | — | US | claimed |
| CN-103601688-A | Synthetic method of trimethoprim impurity | UNIV SICHUAN | 2014-02-26 | — | — | CN | claimed |
| US-20130131182-A1 | PTP1B INHIBITORS, SYNTHESIS THEREOF AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR TREATING TYPE 2 DIABETES MELLITUS | INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2013-05-23 | — | — | US | claimed |
| CN-101987813-B | Chemical total synthesis method for diabetes type II resistant medicament hypnopyrine | INST OCEANOLOGY CHINESE ACAD | 2013-04-17 | — | — | CN | claimed |
| CN-102018692-B | PTP1B inhibitors and synthesis thereof, and application of PTP1B inhibitors in preparation of medicines for treating type 2 diabetes | INST OCEANOLOGY CHINESE ACAD | 2012-11-07 | — | — | CN | claimed |
| CN-102018688-B | PTP1B inhibitor and synthesis and application thereof in preparation of medicine used for treating type II diabetes | INST OCEANOLOGY CHINESE ACAD | 2012-10-10 | — | — | CN | claimed |
| CN-102020621-B | Chemical complete synthesis method of medicine used for treating thrombus heart cerebrovascular disease | INST OCEANOLOGY CHINESE ACAD | 2012-10-03 | — | — | CN | claimed |
| CN-102020540-B | Three protein tyrosine phosphatase 1B (PTP1B) inhibitors and synthesis and application thereof | INST OCEANOLOGY CHINESE ACAD | 2012-09-19 | — | — | CN | claimed |
| CN-102020540-A | Three protein tyrosine phosphatase 1B (PTP1B) inhibitors and synthesis and application thereof | INST OF OCEANOLOGY OF CHINESE ACADEMY OF SCIENCES | 2011-04-20 | — | — | CN | claimed |
| CN-102018692-A | PTP1B inhibitors and synthesis thereof, and application of PTP1B inhibitors to preparation of medicines for treating type 2 diabetes | INST OF OCEANOLOGY OF CHINESE ACADEMY OF SCIENCES | 2011-04-20 | — | — | CN | claimed |
| CN-102020621-A | Chemical complete synthesis method of medicine used for treating thrombus heart cerebrovascular disease | INST OF OCEANOLOGY OF CHINESE ACADEMY OF SCIENCES | 2011-04-20 | — | — | CN | claimed |
| CN-102018688-A | PTP1B inhibitor and synthesis and application thereof in preparation of medicine used for treating type II diabetes | INST OF OCEANOLOGY OF CHINESE ACADEMY OF SCIENCES | 2011-04-20 | — | — | CN | claimed |
| CN-101987813-A | Chemical total synthesis method for type II anti-diabetic medicament hypnopyrine | INST OCEANOLOGY CHINESE ACAD | 2011-03-23 | — | — | CN | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131182-A1 | PTP1B INHIBITORS, SYNTHESIS THEREOF AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR TREATING TYPE 2 DIABETES MELLITUS | PTPA, PPP2CA, PTPRS | ALDH1A1 2001/4885MAPK1 901/4885TUBB1 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.