Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955805 | 0.72 | ALDH1A1 (0.61) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL2955803 | 0.72 | ALDH1A1 (0.61) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL28619926 | 0.69 | MAPK1 (0.50) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL2953452 | 0.69 | ALDH1A1 (0.77) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL5422444 | 0.67 | L3MBTL1 (0.76) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL8485302 | 0.66 | MAPK1 (0.53) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL31684035 | 0.66 | L3MBTL1 (0.74) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL863061 | 0.65 | MAPK1 (0.68) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL2712002 | 0.64 | L3MBTL1 (0.71) | L3MBTL1ALOX15ALDH1A1TSHRGFER | |
| SCHEMBL7180056 | 0.63 | MAPK1 (0.70) | L3MBTL1ALOX15ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866298-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006105127-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-10-05 | — | — | WO | claimed |
| EP-1866298-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006105127-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-10-05 | — | — | WO | disclosed |