SCHEMBL5247237

SCHEMBL5247237

CCCCNCCCCOC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.52
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
EPHX1 P07099 1/20 0.44
NAAA Q02083 1/20 0.42
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5246653 0.98 ACHE (0.55) ACHEALDH1A1TSHREPHX1NAAA
SCHEMBL5245126 0.94 ACHE (0.48) ACHEALDH1A1TSHREPHX1ALOX15
SCHEMBL28771667 0.91 PAOX (0.48) ACHEALDH1A1TSHREPHX1NAAA
SCHEMBL5247574 0.90 ACHE (0.47) ACHEALDH1A1TSHRALOX15
SCHEMBL12521857 0.89 TSHR (0.50) ACHEALDH1A1TSHREPHX1ALOX15
SCHEMBL6289629 0.87 ACHE (0.43) ACHEALDH1A1
SCHEMBL28836986 0.87 ALDH1A1 (0.48) ACHEALDH1A1TSHREPHX1
SCHEMBL23795388 0.86 PAOX (0.47) ACHEALDH1A1TSHREPHX1ALOX15
SCHEMBL5245776 0.86 CYP2C19 (0.44) ACHEALDH1A1TSHREPHX1ALOX15
SCHEMBL6289682 0.85 ACHE (0.43) ACHETSHREPHX1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed