Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 4/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208338 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL30194196 | 0.86 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL28916206 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL31689667 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL21822179 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL9260948 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL9149430 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL5421995 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL3957422 | 0.83 | ALDH1A1 (0.79) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL21822442 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRPLA2G10DAOMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |