Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 13/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289755 | 0.98 | EPHX1 (0.63) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL5248065 | 0.92 | EPHX1 (0.60) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL5244988 | 0.87 | EPHX1 (0.76) | EPHX1ACHE | |
| SCHEMBL5245893 | 0.86 | EPHX1 (0.53) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL5248672 | 0.85 | EPHX1 (0.72) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL5245468 | 0.85 | ACHE (0.59) | EPHX1ACHECHRNB2CHRNA4 | |
| SCHEMBL5246702 | 0.84 | EPHX1 (0.53) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL10812052 | 0.84 | EPHX1 (0.83) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL10812071 | 0.84 | EPHX1 (0.83) | EPHX1ACHECHRNB2CHRNA4CHRM2 | |
| SCHEMBL10817551 | 0.84 | EPHX1 (0.83) | EPHX1ACHECHRNB2CHRNA4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379598-B1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |