SCHEMBL5246702

SCHEMBL5246702

CCNCCOC(=O)NC

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
CHRNB2 P17787 3/20 0.50
CHRNA4 P43681 3/20 0.50
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM5 P08912 1/20 0.50
CYP2D6 P10635 1/20 0.50
CHRM1 P11229 1/20 0.50
NFKB1 P19838 1/20 0.50
CHRM3 P20309 1/20 0.50
MAPK1 P28482 1/20 0.50
CHRNA7 P36544 1/20 0.50
LMNA P02545 1/20 0.48
APEX1 P27695 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACHE P22303 12/20 0.41
SAT1 P21673 1/20 0.35
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5246725 0.88 EPHX1 (0.47) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5251231 0.88 EPHX1 (0.47) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5248065 0.88 EPHX1 (0.60) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL6289755 0.86 EPHX1 (0.63) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5248152 0.84 EPHX1 (0.67) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5249534 0.83 ACHE (0.50) CHRNB2CHRNA4ACHECHRNB4CHRNA3
SCHEMBL5244944 0.82 EPHX1 (0.63) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5245893 0.81 EPHX1 (0.53) EPHX1CHRNB2CHRNA4CHRM2CHRM4
SCHEMBL5245719 0.79
SCHEMBL8018063 0.79 ALDH1A1 (0.43) ACHESAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed
EP-1379598-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-01-14 EP disclosed
WO-2002086000-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed