SCHEMBL524859

SCHEMBL524859

COc1cccc(C=Nc2ccccc2N=Cc2cccc(OC)c2O)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.76
TLR2 O60603 2/20 0.67
TLR1 Q15399 2/20 0.67
TLR6 Q9Y2C9 2/20 0.67
LMNA P02545 2/20 0.64
ALDH1A1 P00352 2/20 0.64
HPGD P15428 1/20 0.64
MAPT P10636 6/20 0.64
CA12 O43570 1/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
G6PD P11413 1/20 0.60
KDM4E B2RXH2 2/20 0.59
MAOB P27338 1/20 0.58
POLB P06746 1/20 0.57
NPC1 O15118 1/20 0.57
HTT P42858 1/20 0.57
RECQL P46063 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ERN1 O75460 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009783 1.00 SMN1; SMN2 (0.76) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL12012954 0.88 SMN1; SMN2 (0.65) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL3776981 0.86 MAPT (0.77) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL12012953 0.86 SMN1; SMN2 (0.63) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL14337416 0.85 MAOB (0.71) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL10090691 0.85 AKR1C3 (0.70) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL22299216 0.82 SMN1; SMN2 (0.58) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL12012960 0.81 MAPT (0.65) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL13187231 0.81 TLR2 (1.00) SMN1; SMN2TLR2TLR1TLR6LMNA
SCHEMBL29819638 0.81 TLR2 (1.00) SMN1; SMN2TLR2TLR1TLR6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015162162-A1 PROCESS FOR DESULPHURISATION OF FUELS QID S.R.L. (IT) 2015-10-29 WO disclosed
EP-2719731-A1 Aqueous coating composition including the reaction product of maleic anhydride with an unsaturated compound and an amine. Akzo Nobel Coatings International B.V. (NL) 2014-04-16 EP disclosed
WO-2014044733-A1 AQUEOUS COATING COMPOSITIONS OF IMPROVED ADHESION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2014-03-27 WO disclosed
EP-2414464-B1 ANTI-CORROSIVE COATING COMPOSITION AKZO NOBEL COATINGS INT BV (NL) 2013-08-28 EP disclosed
EP-2414464-A1 ANTI-CORROSIVE COATING COMPOSITION Akzo Nobel Coatings International B.V. (NL) 2012-02-08 EP disclosed
US-20120025142-A1 ANTI-CORROSIVE COATING COMPOSITION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2012-02-02 US disclosed
WO-2010112605-A1 ANTI-CORROSIVE COATING COMPOSITION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2010-10-07 WO disclosed
EP-1630217-A1 LIGHT-EMITTING DEVICE Takasago International Corporation (JP) 2006-03-01 EP disclosed