Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN1 | O60741 | 12/20 | 0.49 |
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | HCN4 | Q9Y3Q4 | 6/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | HCN3 | Q9P1Z3 | 1/20 | 0.42 |
| ▸ | HCN2 | Q9UL51 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4834372 | 0.99 | HCN1 (0.48) | HCN1TACR1HCN4CHRM3HCN3 | |
| SCHEMBL4835318 | 0.81 | HCN1 (0.51) | HCN1TACR1HCN4 | |
| SCHEMBL5247333 | 0.74 | TACR1 (0.58) | TACR1CHRM3 | |
| Hydrochloric Acid SCHEMBL4837314 | 0.74 | TACR1 (0.57) | TACR1CHRM3 | |
| SCHEMBL8824360 | 0.73 | TACR1 (0.63) | TACR1KCNH2 | |
| Hydrochloric Acid SCHEMBL9391402 | 0.73 | TACR1 (0.61) | TACR1KCNH2 | |
| SCHEMBL5247098 | 0.73 | TACR1 (0.56) | TACR1KCNH2 | |
| SCHEMBL5248023 | 0.72 | TACR1 (0.42) | TACR1 | |
| Hydrochloric Acid SCHEMBL4827359 | 0.72 | TACR1 (0.55) | TACR1KCNH2 | |
| Hydrochloric Acid SCHEMBL4830251 | 0.71 | TACR1 (0.41) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103342-A9 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-10-25 | — | — | WO | disclosed |
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006103342-A2 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2006-10-05 | — | — | WO | disclosed |
| EP-1707564-A2 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-10-04 | — | — | EP | disclosed |