Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4830251 | 0.99 | TACR1 (0.41) | TACR1CYP3A4CYP2D6MITF | |
| SCHEMBL5245485 | 0.94 | TACR1 (0.43) | TACR1 | |
| Hydrochloric Acid SCHEMBL4835695 | 0.93 | TACR1 (0.43) | TACR1 | |
| SCHEMBL5250554 | 0.91 | SLC6A4 (0.45) | TACR1 | |
| Hydrochloric Acid SCHEMBL4827379 | 0.90 | SLC6A4 (0.44) | TACR1 | |
| SCHEMBL5245183 | 0.85 | TACR1 (0.37) | TACR1 | |
| Hydrochloric Acid SCHEMBL4834834 | 0.84 | TACR1 (0.36) | TACR1 | |
| SCHEMBL5249405 | 0.83 | SIGMAR1 (0.40) | CYP3A4 | |
| SCHEMBL5244849 | 0.83 | TACR1 (0.37) | TACR1CYP3A4CYP2D6 | |
| SCHEMBL5248733 | 0.83 | TACR1 (0.37) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |
| EP-1707564-A2 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-10-04 | — | — | EP | disclosed |