Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246087 | 0.93 | CCR1 (0.47) | CCR1SMOPPARGSMN1; SMN2MEN1 | |
| SCHEMBL5248717 | 0.93 | CCR1 (0.43) | CCR1SMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5250048 | 0.92 | EPHX2 (0.46) | CCR1SMN1; SMN2MEN1KMT2AEPHX2 | |
| SCHEMBL5245586 | 0.91 | CCR1 (0.46) | CCR1SMOMEN1KMT2AEPHX2 | |
| SCHEMBL5244539 | 0.91 | SMO (0.44) | CCR1SMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5249146 | 0.90 | CCR1 (0.51) | CCR1MEN1KMT2AMMP13ABCB1 | |
| SCHEMBL5247431 | 0.90 | RIPK1 (0.44) | CCR1SMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5248465 | 0.90 | CCR1 (0.46) | CCR1PPARGSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5244893 | 0.89 | MAPK14 (0.48) | CCR1PPARGEPHX2PTGER4MAPK14 | |
| SCHEMBL5248289 | 0.89 | CCR1 (0.40) | CCR1SMOMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |