SCHEMBL5249042

SCHEMBL5249042

CCCCNCCOCCOCCOC(=O)NC

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.56
ACHE P22303 12/20 0.53
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5248040 1.00 EPHX1 (0.56) EPHX1ACHEKDM4EALDH1A1SMN1; SMN2
SCHEMBL5244944 0.90 EPHX1 (0.63) EPHX1ACHEALDH1A1SMN1; SMN2TSHR
SCHEMBL5247571 0.87 EPHX1 (0.61) EPHX1ACHESMN1; SMN2CYP2D6
SCHEMBL5247229 0.87 ACHE (0.73) EPHX1ACHEKDM4EALDH1A1SMN1; SMN2
SCHEMBL5245754 0.87 ACHE (0.73) EPHX1ACHEKDM4EALDH1A1SMN1; SMN2
SCHEMBL5249162 0.86 EPHX1 (0.69) EPHX1ACHEALDH1A1SMN1; SMN2CYP2D6
SCHEMBL5246582 0.85 ACHE (0.61) ACHEKDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL5246760 0.85 ACHE (0.61) ACHEKDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL5251231 0.84 EPHX1 (0.47) EPHX1ACHEKDM4EALDH1A1SMN1; SMN2
SCHEMBL5246725 0.84 EPHX1 (0.47) EPHX1ACHEKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed