SCHEMBL5249162

SCHEMBL5249162

CCCCNCCCOC(=O)NC

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.69
ACHE P22303 14/20 0.56
CHRNB2 P17787 2/20 0.46
CHRNA4 P43681 2/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CYP2D6 P10635 1/20 0.46
CHRM1 P11229 1/20 0.46
NFKB1 P19838 1/20 0.46
CHRM3 P20309 1/20 0.46
MAPK1 P28482 1/20 0.46
CHRNA7 P36544 1/20 0.46
LMNA P02545 1/20 0.44
APEX1 P27695 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5248672 0.94 EPHX1 (0.72) EPHX1ACHECHRNB2CHRNA4CHRM2
SCHEMBL5247571 0.93 EPHX1 (0.61) EPHX1ACHECHRNB2CHRNA4CHRM2
SCHEMBL5244988 0.93 EPHX1 (0.76) EPHX1ACHE
SCHEMBL5244944 0.92 EPHX1 (0.63) EPHX1ACHECHRNB2CHRNA4CHRM2
SCHEMBL5248065 0.86 EPHX1 (0.60) EPHX1ACHECHRNB2CHRNA4CHRM2
SCHEMBL5249042 0.86 EPHX1 (0.56) EPHX1ACHECYP2D6SMN1; SMN2ALDH1A1
SCHEMBL5248040 0.86 EPHX1 (0.56) EPHX1ACHECYP2D6SMN1; SMN2ALDH1A1
SCHEMBL968307 0.86
SCHEMBL6289600 0.85 ACHE (0.79) EPHX1ACHE
SCHEMBL1170169 0.84 EPHX1 (0.96) EPHX1ACHECHRNB2CHRNA4CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024091918-A2 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2024-05-02 WO disclosed
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed