Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250384 | 1.00 | ALOX5 (0.38) | ALOX5OPRM1OPRK1POLBCTSK | |
| SCHEMBL5252722 | 1.00 | ALOX5 (0.38) | ALOX5OPRM1OPRK1POLBCTSK | |
| SCHEMBL5250663 | 0.84 | NPC1 (0.42) | ALOX5OPRM1OPRK1POLBCTSK | |
| SCHEMBL5246383 | 0.78 | GABBR2 (0.40) | POLBKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL5245436 | 0.78 | GABBR2 (0.40) | POLBKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL5246081 | 0.78 | GABBR2 (0.40) | POLBKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL5247882 | 0.77 | GAA (0.33) | KDM4ECES2CES1KMT2A | |
| SCHEMBL5246673 | 0.77 | ALOX5 (0.40) | ALOX5POLBCYP2C9CYP2C19LMNA | |
| SCHEMBL5248147 | 0.77 | GAA (0.33) | KDM4ECES2CES1KMT2A | |
| SCHEMBL5248608 | 0.77 | GAA (0.33) | KDM4ECES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406605-B1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2007-09-19 | — | — | EP | disclosed |
| EP-1406605-A4 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2005-10-26 | — | — | EP | disclosed |
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION | 2005-03-24 | — | — | US | disclosed |
| US-6841569-B2 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1406605-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK Corporation (KR) | 2004-04-14 | — | — | EP | disclosed |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-04-24 | — | — | US | disclosed |
| WO-2003000247-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORPORATION (KR) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | ALOX5 1146/4885OPRM1 576/4885OPRK1 668/4885 |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | ALOX5 1146/4885OPRM1 576/4885OPRK1 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.