SCHEMBL5249727

SCHEMBL5249727

[c]1ccc(C(c2cc[c]cc2)c2cc[c]cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP19A1 P11511 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10839213 0.88 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3
SCHEMBL3840843 0.88 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3
SCHEMBL11046872 0.84 TYR (0.39) CYP19A1
SCHEMBL4989486 0.76 LMNA (0.41) SLC6A2SLC6A4SLC6A3CYP19A1
SCHEMBL27871094 0.76 TYR (0.37)
SCHEMBL21459 0.73
SCHEMBL5698541 0.73
SCHEMBL9635699 0.73
SCHEMBL1480750 0.73
SCHEMBL2058608 0.73 ESR1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831762-A1 BLOCKED ALIPHATIC THIOL STABILIZERS FOR PHOTOTHERMOGRAPHIC MATERIALS Carestream Health, Inc. (US) 2007-09-12 EP disclosed
US-7169543-B2 Blocked aliphatic thiol stabilizers for photothermographic materials EASTMAN KODAK COMPANY (US) 2007-01-30 US disclosed
WO-2006071585-A1 BLOCKED ALIPHATIC THIOL STABILIZERS FOR PHOTOTHERMOGRAPHIC MATERIALS CARESTREAM HEALTH, INC. (US) 2006-07-06 WO disclosed
US-20060141403-A1 Blocked aliphatic thiol stabilizers for photothermographic materials EASTMAN KODAK COMPANY 2006-06-29 US disclosed