⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525777 | 0.90 | — | — | |
| SCHEMBL29001316 | 0.87 | LMNA (0.38) | — | |
| SCHEMBL14742718 | 0.87 | — | — | |
| SCHEMBL15282675 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL14544330 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL94683 | 0.77 | — | — | |
| SCHEMBL2680591 | 0.76 | — | — | |
| SCHEMBL28902420 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL20471562 | 0.74 | — | — | |
| SCHEMBL8991840 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117925296-A | High-performance shallow sulfur antiwear extreme pressure additive and preparation method thereof | 银川兰达化工科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117165210-A | EVA adhesive film and preparation method thereof | 福建惠亿美环保材料科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| EP-2625216-B1 | POLYMERISABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | NOVARTIS AG (CH) | 2019-06-05 | — | — | EP | claimed |
| CN-108676179-A | A kind of polyethylene glycols chemistry hydrogel and preparation method thereof based on enzyme crosslinking | 复旦大学 | 2018-10-19 | — | — | CN | claimed |
| US-9109091-B2 | Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups | NOVARTIS AG (CH) | 2015-08-18 | — | — | US | claimed |
| US-20150152228-A1 | POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | ALCON INC. (CH) | 2015-06-04 | — | — | US | claimed |
| US-8993651-B2 | Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups | NOVARTIS AG (CH) | 2015-03-31 | — | — | US | claimed |
| EP-2625216-A1 | POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | Novartis AG (CH) | 2013-08-14 | — | — | EP | claimed |
| WO-2012047961-A1 | POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | claimed |
| US-20120088843-A1 | POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | ALCON INC. (CH) | 2012-04-12 | — | — | US | claimed |
| EP-1214933-A1 | METHOD FOR MODULATING THE METABOLISM OF NITROGEN OXIDES, COMPOSITIONS THEREFOR (AND VARIANTS) AND METHOD FOR ACTING ON A PATIENT'S ORGANISM NECESSITATING THE METABOLISM OF NITROGEN OXIDES TO BE CORRECTED | Institut Molekulyarnoi Genetiki Rossiiskoi Akademii Nauk ( Img Ran ) (RU) | 2002-06-19 | — | — | EP | claimed |
| US-4992293-A | Digestible fat substitutes in foods; side effect reduction | NABISCO BRANDS, INC. (US) | 1991-02-12 | — | — | US | claimed |
| EP-3635450-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-05-08 | — | — | EP | disclosed |
| CN-117925296-A | High-performance shallow sulfur antiwear extreme pressure additive and preparation method thereof | 银川兰达化工科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117925296-A | High-performance shallow sulfur antiwear extreme pressure additive and preparation method thereof | 银川兰达化工科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117165210-A | EVA adhesive film and preparation method thereof | 福建惠亿美环保材料科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-02-02 | — | — | US | disclosed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | disclosed |
| US-20020115819-A1 | Polymerizable compositions for manufacturing transparent polymeric substrates, resulting transparent polymeric substrates and their applications in the optical field | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2002-08-22 | — | — | US | disclosed |
| US-4992293-A | Digestible fat substitutes in foods; side effect reduction | NABISCO BRANDS, INC. (US) | 1991-02-12 | — | — | US | disclosed |