Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018772 | 1.00 | HSD17B10 (0.42) | HSD17B10ALOX15TSHRKMT2ABLM | |
| SCHEMBL6019809 | 0.84 | CYP3A4 (0.43) | ALOX15TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6019364 | 0.84 | ALDH1A1 (0.44) | ALOX15TSHRKMT2AGRM2POLB | |
| SCHEMBL11891370 | 0.71 | ALOX15 (0.41) | HSD17B10ALOX15TSHRKMT2ABLM | |
| SCHEMBL6018783 | 0.71 | — | — | |
| SCHEMBL25269677 | 0.70 | HDAC6 (0.46) | HSD17B10ALOX15TSHRKMT2ABLM | |
| Hydrochloric Acid SCHEMBL11031655 | 0.70 | ALOX15 (0.40) | HSD17B10ALOX15TSHRKMT2ABLM | |
| SCHEMBL14835561 | 0.68 | ALDH1A1 (0.44) | HSD17B10ALOX15TSHRKMT2AALOX12 | |
| SCHEMBL11030834 | 0.68 | ALOX15 (0.38) | HSD17B10ALOX15TSHRKMT2ABLM | |
| SCHEMBL6019489 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831175-A1 | DIHYDRONEPETALACTAMS AND N-SUBSTITUTED DERIVATIVES THEREOF | E.I.Du pont de nemours and company (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006072037-A1 | DIHYDRONEPETALACTAMS AND N-SUBSTITUTED DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |