Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.34 |
| ▸ | PLK2 | Q9NYY3 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244405 | 0.95 | KMT2A (0.38) | SMPD1TP53BRD4ACKR3MEN1 | |
| SCHEMBL5243944 | 0.93 | SMPD1 (0.39) | SMPD1TP53BRD4ACKR3PLK1 | |
| SCHEMBL5247498 | 0.92 | SMPD1 (0.39) | SMPD1TP53BRD4ACKR3PLK1 | |
| SCHEMBL5247607 | 0.91 | KMT2A (0.43) | TP53ACKR3MEN1KMT2A | |
| SCHEMBL5244829 | 0.90 | BRD4 (0.37) | SMPD1TP53BRD4ACKR3MEN1 | |
| SCHEMBL5250028 | 0.90 | SMPD1 (0.33) | SMPD1TP53ACKR3 | |
| SCHEMBL5245878 | 0.89 | BRD4 (0.42) | TP53BRD4KMT2A | |
| SCHEMBL5247507 | 0.89 | SMPD1 (0.38) | SMPD1TP53BRD4ACKR3KMT2A | |
| SCHEMBL5248452 | 0.89 | BRD4 (0.36) | SMPD1TP53BRD4ACKR3CNR2 | |
| SCHEMBL5248542 | 0.88 | BRD4 (0.36) | SMPD1TP53BRD4ACKR3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |