⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827515 | 0.78 | — | — | |
| SCHEMBL11000641 | 0.78 | — | — | |
| SCHEMBL1827512 | 0.78 | — | — | |
| SCHEMBL7362688 | 0.75 | — | — | |
| SCHEMBL397456 | 0.75 | — | — | |
| SCHEMBL7362692 | 0.75 | — | — | |
| SCHEMBL9226139 | 0.75 | — | — | |
| SCHEMBL18099936 | 0.75 | — | — | |
| Methylene Chloride SCHEMBL28623150 | 0.73 | TRPA1 (0.38) | — | |
| SCHEMBL628752 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0912467-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000375-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1998-01-08 | — | — | WO | claimed |
| EP-0323625-B1 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| JP-1203350-A | — | — | None | — | — | JP | disclosed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-12018002-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC (US) | 2024-06-25 | — | — | US | disclosed |
| US-11912714-B2 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230364121-A1 | NIRAN INTERFERING DRUGS FOR SARS-COV-2 MUTANT THERAPY | Atea Pharmaceuticals, Inc. (US) | 2023-11-16 | — | — | US | disclosed |
| EP-0055427-B1 | PROCESS FOR THE PRODUCTION OF MONOCHLOROMETHYL KETONES | BAYER AG (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0055427-A1 | Process for the production of monochloromethyl ketones | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4275200-A | CONDENSATION OF CARBAMIC ESTERS WITH X-HALOGEN CARBONYL COMPOUNDS | AGFA-GEVAERT, A.G. (DE) | 1981-06-23 | — | — | US | disclosed |
| US-4240983-A | HALOGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |
| US-4164579-A | ANTI-ULCER AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1979-08-14 | — | — | US | disclosed |
| US-4064244-A | ANOREXIGENIC AGENTS, ANTIMIGRAINE AGENTS | SANDOZ LTD. (CH) | 1977-12-20 | — | — | US | disclosed |
| US-4059447-A | Photographic material containing oxazolinone-2 couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |