SCHEMBL525228

SCHEMBL525228

NCCOCC(N)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.55
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
GSR P00390 2/20 0.45
CTH P32929 1/20 0.42
LMNA P02545 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC7A11 Q9UPY5 1/20 0.41
SLC1A5 Q15758 1/20 0.40
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
GRM1 Q13255 2/20 0.38
GRM2 Q14416 2/20 0.38
SLC7A5 Q01650 1/20 0.38
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479185 1.00 NOS3 (0.55) NOS3NOS1NOS2GSRCTH
SCHEMBL31688706 1.00 NOS3 (0.55) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL524956 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL6873225 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL524957 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
SCHEMBL890600 0.96 NOS3 (0.51) NOS3NOS1NOS2GSRCTH
SCHEMBL890474 0.96 NOS3 (0.51) NOS3NOS1NOS2GSRCTH
SCHEMBL4018310 0.87 GSR (0.52) NOS3NOS1NOS2GSRCTH
SCHEMBL1316628 0.87 GSR (0.52) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL21332552 0.85 NOS3 (0.50) NOS3NOS1NOS2GSRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108136038-A Conjugates comprising peptide groups and methods related thereto 乐高化学生物科学股份有限公司 2018-06-08 CN claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
CN-108136038-A Conjugates comprising peptide groups and methods related thereto 乐高化学生物科学股份有限公司 2018-06-08 CN disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-9637520-B2 Template-fixed peptidomimetics with CXCR7 modulating activity POLYPHOR AG (CH) 2017-05-02 US disclosed
CN-102844327-B Template-fixed peptidomimetics with CXCR7 modulatory activity 波利弗尔股份公司 2016-10-26 CN disclosed
CN-102712676-B There is the peptidomimetic that the template of CCR10 antagonistic activity is fixing 波利弗尔股份公司 2016-10-26 CN disclosed
EP-0775160-A1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATECH, INC. (US) 1997-05-28 EP disclosed
WO-1996030055-A2 RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY DIATIDE, INC. (US) 1996-10-03 WO disclosed
EP-0720621-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES Diatide, Inc. (US) 1996-07-10 EP disclosed
WO-1996012499-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-05-02 WO disclosed
WO-1996004308-A1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATECH, INC. (US) 1996-02-15 WO disclosed
EP-0649434-A1 RADIOACTIVELY-LABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES Diatide, Inc. (US) 1995-04-26 EP disclosed
WO-1995003330-A1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATECH, INC. (US) 1995-02-02 WO disclosed
WO-1995000553-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1995-01-05 WO disclosed
WO-1994000489-A2 RADIOACTIVELY-LABELED SOMATOSTANTIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1994-01-06 WO disclosed