Sugi Predict

Sugi Predict / Compounds / SCHEMBL479185

SCHEMBL479185

SCHEMBL479185

NCCOC[C@H](N)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS3 P29474 2/20 0.55
▸ NOS1 P29475 2/20 0.55
▸ NOS2 P35228 2/20 0.55
▸ GSR P00390 2/20 0.45
▸ CTH P32929 1/20 0.42
▸ LMNA P02545 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ SLC7A11 Q9UPY5 1/20 0.41
▸ SLC1A5 Q15758 1/20 0.40
▸ GRIK1 P39086 2/20 0.38
▸ GRIK2 Q13002 2/20 0.38
▸ GRM1 Q13255 2/20 0.38
▸ GRM2 Q14416 2/20 0.38
▸ SLC7A5 Q01650 1/20 0.38
▸ GRM8 O00222 1/20 0.38
▸ GRM6 O15303 1/20 0.38
▸ GRIN2D O15399 1/20 0.38
▸ GRIN3B O60391 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31688706 1.00 NOS3 (0.55) NOS3NOS1NOS2GSRCTH
SCHEMBL525228 1.00 NOS3 (0.55) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL524956 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL6873225 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL524957 0.98 NOS3 (0.53) NOS3NOS1NOS2GSRCTH
SCHEMBL890600 0.96 NOS3 (0.51) NOS3NOS1NOS2GSRCTH
SCHEMBL890474 0.96 NOS3 (0.51) NOS3NOS1NOS2GSRCTH
SCHEMBL4018310 0.87 GSR (0.52) NOS3NOS1NOS2GSRCTH
SCHEMBL1316628 0.87 GSR (0.52) NOS3NOS1NOS2GSRCTH
Hydrochloric Acid SCHEMBL21332552 0.85 NOS3 (0.50) NOS3NOS1NOS2GSRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135048-A1 Fibroblast activation protein compound or salt with albumin dual-binding function NATIONAL ATOMIC RESEARCH INSTITUTE (TW) 2025-05-01 — — US claimed
EP-4545098-A1 FIBROBLAST ACTIVATION PROTEIN COMPOUND OR SALT WITH ALBUMIN DUAL-BINDING FUNCTION National Atomic Research Institute (TW) 2025-04-30 — — EP claimed
US-20220226496-A1 LIGAND-DRUG CONJUGATE INCLUDING LINKER HAVING TRIS STRUCTURE LEGOCHEM BIOSCIENCES, INC. (KR) 2022-07-21 — — US claimed
EP-3964236-A1 LIGAND-DRUG CONJUGATE INCLUDING LINKER HAVING TRIS STRUCTURE LegoChem Biosciences, Inc. (KR) 2022-03-09 — — EP claimed
US-11167040-B2 Conjugates comprising peptide groups and methods related thereto LEGOCHEM BIOSCIENCES, INC. (KR) 2021-11-09 — — US claimed
EP-3380125-A1 CONJUGATES COMPRISING PEPTIDE GROUPS AND METHODS RELATED THERETO LegoChem Biosciences, Inc. (KR) 2018-10-03 — — EP claimed
CN-108136038-A Conjugates comprising peptide groups and methods related thereto 乐高化学生物科学股份有限公司 2018-06-08 — — CN claimed
WO-2017089894-A1 CONJUGATES COMPRISING PEPTIDE GROUPS AND METHODS RELATED THERETO LEGOCHEM BIOSCIENCES, INC. (KR) 2017-06-01 — — WO claimed
EP-2961730-A2 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS XenoPort, Inc. (US) 2016-01-06 — — EP claimed
US-20150158809-A9 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS XENOPORT, INC. (US) 2015-06-11 — — US claimed
WO-2014134005-A2 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS XENOPORT, INC. (US) 2014-09-04 — — WO claimed
US-20140243544-A1 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS XENOPORT, INC. (US) 2014-08-28 — — US claimed
US-8299291-B2 Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs XENOPORT, INC. (US) 2012-10-30 — — US claimed
US-8062870-B2 Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs XENOPORT, INC. (US) 2011-11-22 — — US claimed
EP-1017358-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2004-08-11 — — EP claimed
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 — — EP claimed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 — — US claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 — — WO claimed
JP-11029414-A — — None — — JP disclosed
US-4716242-A ANTITUMOR AGENTS ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) 1987-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11167040-B2 Conjugates comprising peptide groups and methods related thereto DAO, LPO, TYRO3 NOS3 334/4885NOS1 337/4885NOS2 229/4885
US-20150158809-A9 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS CPS1, CA7, NAAA NOS3 1112/4885NOS1 1004/4885NOS2 1286/4885
US-20220226496-A1 LIGAND-DRUG CONJUGATE INCLUDING LINKER HAVING TRIS STRUCTURE TNFSF10, TNFRSF9, ANTXR2 NOS3 4769/4885NOS1 4597/4885NOS2 4604/4885
US-20140243544-A1 METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS CPS1, CA7, NAAA NOS3 1112/4885NOS1 1004/4885NOS2 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.