Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22205248 | 0.88 | CXCR4 (0.61) | CXCR4HRH4MC4RKDM4ECHKA | |
| SCHEMBL29462386 | 0.87 | FAAH (0.54) | FAAHCXCR4KDM4ETDP1ACHE | |
| SCHEMBL5255062 | 0.87 | FAAH (0.54) | FAAHCXCR4KDM4ETDP1ACHE | |
| Hydrochloric Acid SCHEMBL29604571 | 0.86 | CXCR4 (0.59) | CXCR4HRH4MC4RKDM4ECHKA | |
| Bromide SCHEMBL29604007 | 0.86 | CXCR4 (0.59) | CXCR4HRH4MC4RKDM4ECHKA | |
| SCHEMBL839038 | 0.83 | FAAH (0.53) | FAAHCXCR4HRH4KDM4ETDP1 | |
| SCHEMBL13940602 | 0.83 | FAAH (0.51) | FAAHCXCR4KDM4ETDP1ACHE | |
| SCHEMBL14851189 | 0.81 | HTR3E (0.53) | CXCR4HRH4MC4RKDM4EACHE | |
| SCHEMBL15980623 | 0.81 | CXCR4 (0.46) | FAAHCXCR4HRH4MC4RKDM4E | |
| SCHEMBL840048 | 0.81 | KMT2A (0.59) | FAAHCXCR4KDM4EACHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268431-B1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH CORP (US) | 2007-08-29 | — | — | EP | disclosed |