Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 14/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258097 | 0.84 | ALOX15 (0.51) | ALOX15LMNAPOLBNPC1RAB9A | |
| SCHEMBL3989236 | 0.71 | ALOX15 (0.94) | ALOX15LMNANPC1RAB9A | |
| SCHEMBL2907641 | 0.71 | ALOX15 (1.00) | ALOX15LMNANPC1RAB9A | |
| SCHEMBL31453202 | 0.69 | ALOX15 (0.57) | ALOX15LMNATDP1MAPTSMN1; SMN2 | |
| SCHEMBL22939286 | 0.69 | ALOX15 (0.57) | ALOX15LMNAMAPT | |
| SCHEMBL22257192 | 0.68 | ALOX15 (0.59) | ALOX15LMNANPC1RAB9A | |
| SCHEMBL2909325 | 0.67 | ALOX15 (1.00) | ALOX15LMNANPC1 | |
| SCHEMBL22257199 | 0.67 | ALOX15 (0.55) | ALOX15LMNA | |
| SCHEMBL22257202 | 0.67 | ALOX15 (0.55) | ALOX15LMNA | |
| SCHEMBL22257174 | 0.67 | ALOX15 (0.50) | ALOX15LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794130-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006032852-A1 | PYRAZOLE COMPOUNDS USEFUL UIN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-03-30 | — | — | WO | disclosed |