SCHEMBL3989236

SCHEMBL3989236

CCCCNC(=O)n1ccc(C(=O)Nc2ccc(F)cc2Cl)n1

nearest known ligand 0.94

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 15/20 0.94
KMT2A Q03164 2/20 0.44
F2 P00734 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2907641 0.97 ALOX15 (1.00) ALOX15KMT2AF2NPC1RAB9A
SCHEMBL2909325 0.86 ALOX15 (1.00) ALOX15KMT2AF2NPC1ALDH1A1
SCHEMBL6003857 0.78 ALOX15 (0.69) ALOX15KMT2ANPC1RAB9ALMNA
SCHEMBL6454874 0.74 ALOX15 (0.57) ALOX15LMNA
SCHEMBL6004365 0.73 ALOX15 (0.61) ALOX15KMT2AF2NPC1RAB9A
SCHEMBL6002665 0.73 ALOX15 (0.64) ALOX15NPC1RAB9AALDH1A1
SCHEMBL5254653 0.71 ALOX15 (0.55) ALOX15NPC1RAB9ALMNA
SCHEMBL6004838 0.69 ALOX15 (0.50) ALOX15KMT2AF2NPC1RAB9A
SCHEMBL162022 0.69 ALOX15 (0.47) ALOX15KMT2A
SCHEMBL5258097 0.69 ALOX15 (0.51) ALOX15NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090247634-A1 Methods for identifying modulators of eoxin formation CLAESSON HANS-ERIK 2009-10-01 US disclosed
EP-2035573-A1 METHODS FOR IDENTIFYING MODULATORS OF EOXIN FORMATION Biolipox AB (SE) 2009-03-18 EP disclosed
WO-2008001079-A1 METHODS FOR IDENTIFYING MODULATORS OF EOXIN FORMATION BIOLIPOX AB (SE) 2008-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247634-A1 Methods for identifying modulators of eoxin formation LTA4H, LTC4S, LTB4R2 ALOX15 8/4885KMT2A 3941/4885F2 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.