Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.30 |
| ▸ | SDC2 | P34741 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185410 | 0.92 | CASR (0.35) | SMN1; SMN2HTR2CSLC6A4SSTR4GSTO1 | |
| SCHEMBL5256146 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2HTR2CSLC6A4HDAC3HDAC1 | |
| SCHEMBL5257291 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2SDCBPSDC2KMT2A | |
| SCHEMBL5259863 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1SDCBPSDC2KMT2A | |
| SCHEMBL5185310 | 0.74 | ALDH1A1 (0.35) | SMN1; SMN2HTR2CSLC6A4ALDH1A1KMT2A | |
| SCHEMBL5253493 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2HDAC3HDAC1HDAC2KDM4E | |
| SCHEMBL5257722 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2KDM4E | |
| SCHEMBL5254786 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL5187917 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EALDH1A1ELANEKMT2A | |
| SCHEMBL5185693 | 0.67 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |