Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187022 | 0.96 | MTNR1A (0.45) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5257722 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5185693 | 0.87 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5185323 | 0.85 | L3MBTL1 (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5253493 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4ECYP1A2RECQL | |
| SCHEMBL5185595 | 0.78 | PTGES (0.60) | SMN1; SMN2CYP1A2KMT2ATP53GAA | |
| SCHEMBL5254786 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4ECYP1A2RECQL | |
| SCHEMBL5185657 | 0.76 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5185410 | 0.73 | CASR (0.35) | SMN1; SMN2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL5257291 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288549-B2 | Heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | AVENTIS PHARMA S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-20050245505-A1 | Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | ENTASIS THERAPEUTICS LIMITED (GB) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245505-A1 | Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | FDPS, MRPL21, DHPS | SMN1; SMN2 4184/4885ALDH1A1 1565/4885MAPT 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.