Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225642 | 0.91 | ITGB1 (0.36) | P2RX7P2RX3HDAC3HDAC1HDAC6 | |
| SCHEMBL5257897 | 0.91 | CA12 (0.36) | CA12CA9CA7CA14CA2 | |
| SCHEMBL5259962 | 0.90 | CA12 (0.35) | CA12CA9CA7CA14CA2 | |
| SCHEMBL5257627 | 0.85 | CA12 (0.37) | CA12CA9CA7CA14CA2 | |
| SCHEMBL5255316 | 0.84 | LCK (0.37) | P2RX7P2RX3ACACB | |
| SCHEMBL5228649 | 0.81 | ITGB1 (0.37) | P2RX7P2RX3HDAC3HDAC1HDAC6 | |
| SCHEMBL5228794 | 0.81 | ITGB1 (0.38) | P2RX7HDAC3HDAC1HDAC6TRPV1 | |
| SCHEMBL5258334 | 0.79 | NAMPT (0.36) | P2RX7P2RX3EGFRALDH1A1 | |
| SCHEMBL5255287 | 0.79 | HDAC3 (0.34) | P2RX7P2RX3HDAC3HDAC1HDAC6 | |
| SCHEMBL5262134 | 0.78 | CIT (0.39) | ACACBHDAC3HDAC1HDAC6TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |