SCHEMBL5258334 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NAMPT	P43490	1/20	0.36

▸	P2RX3	P56373	10/20	0.35

▸	P2RX7	Q99572	4/20	0.34

▸	EGFR	P00533	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	TP53	P04637	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	F2	P00734	2/20	0.32

▸	PRSS1	P07477	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5227174	0.93	NAMPT (0.37)	NAMPTP2RX3P2RX7ALDH1A1TP53
SCHEMBL5255103	0.86	P2RX7 (0.37)	P2RX7ALDH1A1TP53SMN1; SMN2F2
SCHEMBL5255316	0.83	LCK (0.37)	P2RX3P2RX7SMN1; SMN2F2PRSS1
SCHEMBL5259962	0.81	CA12 (0.35)	P2RX7EGFRALDH1A1
SCHEMBL5257897	0.81	CA12 (0.36)	P2RX3P2RX7EGFRALDH1A1
SCHEMBL5225880	0.79	P2RX7 (0.38)	P2RX7ALDH1A1TP53SMN1; SMN2F2
SCHEMBL5258338	0.79	NAMPT (0.37)	NAMPTALDH1A1TP53SMN1; SMN2
SCHEMBL5255283	0.79	CA12 (0.37)	P2RX3P2RX7EGFRALDH1A1
SCHEMBL5262133	0.75	CIT (0.39)	EGFRALDH1A1
SCHEMBL5262134	0.75	CIT (0.39)	EGFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1622867-B1	N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS	ALMIRALL LAB (ES)	2007-09-19	—	—	EP	claimed