Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4842640 | 0.94 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL5257529 | 0.91 | MEN1 (0.42) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL5260102 | 0.86 | MAPK1 (0.40) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL4842600 | 0.85 | CYP2D6 (0.40) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL5259203 | 0.84 | TSHR (0.49) | — | |
| SCHEMBL4842028 | 0.84 | MAPK1 (0.46) | KMT2AMEN1LMNAMAPK1MAPT | |
| SCHEMBL5256838 | 0.84 | KMT2A (0.39) | KMT2AMEN1MAPK1PRMT5GAA | |
| SCHEMBL4842226 | 0.83 | KDM1A (0.40) | ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL4838763 | 0.83 | MEN1 (0.42) | KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL4840566 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2ALMNAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |