Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257529 | 0.94 | MEN1 (0.42) | CYP2D6CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4842640 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL4840566 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ALMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL4838222 | 0.88 | ACHE (0.41) | KCNH2 | |
| Trifluoroacetic Acid SCHEMBL4834961 | 0.88 | CDK4 (0.35) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5255347 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL5258414 | 0.83 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL5260102 | 0.83 | MAPK1 (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL4834051 | 0.83 | KDM4E (0.45) | ALDH1A1MEN1KMT2ACASR | |
| Trifluoroacetic Acid SCHEMBL4834992 | 0.82 | HDAC3 (0.36) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | CYP2D6 1106/4885CYP1A2 1343/4885CYP2C9 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.