Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253702 | 0.92 | HTR1A (0.38) | MEN1KMT2AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL4139603 | 0.90 | MEN1 (0.39) | MEN1KMT2ALIG1NPC1POLB | |
| SCHEMBL4136367 | 0.83 | BCHE (0.42) | NPC1RAB9AALDH1A1BCHEGAA | |
| SCHEMBL5256420 | 0.83 | BCHE (0.42) | NPC1RAB9AALDH1A1BCHEGAA | |
| SCHEMBL5185631 | 0.82 | KMT2A (0.39) | MEN1KMT2AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL4696919 | 0.81 | MEN1 (0.36) | MEN1KMT2ALIG1HTR1ASLC6A2 | |
| SCHEMBL5330841 | 0.80 | TSHR (0.40) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL5257111 | 0.78 | TSHR (0.38) | MEN1KMT2ALIG1POLBALDH1A1 | |
| SCHEMBL5186922 | 0.75 | BCHE (0.38) | NPC1POLBRAB9AALDH1A1BCHE | |
| SCHEMBL4144345 | 0.75 | MEN1 (0.38) | MEN1KMT2ALIG1POLBCXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1399444-A2 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100860-A2 | HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-12-19 | — | — | WO | disclosed |