Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765440 | 0.89 | TGFBR1 (0.35) | — | |
| SCHEMBL5258600 | 0.87 | OPRD1 (0.30) | OPRD1 | |
| SCHEMBL4763292 | 0.81 | KDM4E (0.40) | OPRD1 | |
| SCHEMBL4771399 | 0.80 | TGFBR1 (0.37) | — | |
| SCHEMBL4763649 | 0.79 | — | — | |
| SCHEMBL4766453 | 0.79 | CYP3A4 (0.32) | — | |
| SCHEMBL4770965 | 0.78 | TGFBR1 (0.33) | — | |
| SCHEMBL4767703 | 0.78 | PDE10A (0.32) | — | |
| SCHEMBL4770139 | 0.77 | — | — | |
| SCHEMBL4790982 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648899-B1 | IMIDAZO-PYRIMIDINES AND TRIAZOLO-PYRIMIDINES: BENZODIAZEPINE RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2007-01-03 | — | — | EP | claimed |