SCHEMBL525624

SCHEMBL525624

OCCOCCOCCOCCOCCOCC(O)(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036436 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL4107336 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL9053026 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL4106728 0.95
SCHEMBL5860527 0.81 MEN1 (0.50) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL7919973 0.79 MEN1 (0.61) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL7898330 0.76 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL26397994 0.76 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL11954753 0.76 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL695304 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516083-B2 Nucleophilic catalysts for oxime linkage TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-01-06 US disclosed
US-20240335549-A1 THERAPEUTIC PROTEINS WITH INCREASED HALF-LIFE AND METHODS OF PREPARING SAME BAXALTA INCORPORATED (US) 2024-10-10 US disclosed
WO-2024132865-A1 ANTIMICROBIAL COMPOUND, PROCESS FOR PREPARING SAME AND USE OF THE ANTIMICROBIAL COMPOUND FOR PREPARING A COSMETIC OR PHARMACEUTICAL COMPOSITION AEROCHEMICA DR. DEPPE GMBH (DE) 2024-06-27 WO disclosed
EP-4389219-A1 ANTIMICROBIAL COMPOUND, METHOD FOR ITS PREPARATION AND USE OF THE ANTIMICROBIAL COMPOUND FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL COMPOSITION Aerochemica Dr. Deppe GmbH (DE) 2024-06-26 EP disclosed
US-11564992-B2 Nucleophilic catalysts for oxime linkage TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-01-31 US disclosed
EP-4023247-A1 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE Takeda Pharmaceutical Company Limited (JP) 2022-07-06 EP disclosed
EP-4019049-A1 METHODS FOR PREPARING THERAPEUTIC PROTEIN-POLYMER CONJUGATES Takeda Pharmaceutical Company Limited (JP) 2022-06-29 EP disclosed
US-20220175939-A1 THERAPEUTIC PROTEINS WITH INCREASED HALF-LIFE AND METHODS OF PREPARING SAME BAXALTA INCORPORATED (US) 2022-06-09 US disclosed
EP-2849795-B1 METHODS FOR PREPARING THERAPEUTIC PROTEIN-POLYMER CONJUGATES TAKEDA PHARMACEUTICALS CO (JP) 2022-04-06 EP disclosed
EP-3505186-B1 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE TAKEDA PHARMACEUTICALS CO (JP) 2022-01-12 EP disclosed
EP-2459224-A2 BLOOD COAGULATION PROTEIN CONJUGATES Baxter International Inc (US) 2012-06-06 EP disclosed
EP-2459226-A2 GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS Lipoxen Technologies Limited (GB) 2012-06-06 EP disclosed
US-20120035344-A1 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE BAXTER HEALTHCARE S.A. (CH) 2012-02-09 US disclosed
WO-2012016131-A1 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE BAXTER INTERNATIONAL INC. (US) 2012-02-02 WO disclosed
WO-2011012850-A9 GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS LIPOXEN TECHNOLOGIES LIMITED (GB) 2011-05-12 WO disclosed
WO-2011017055-A2 BLOOD COAGULATION PROTEIN CONJUGATES BAXTER INTERNATIONAL INC. (US) 2011-02-10 WO disclosed
WO-2011012850-A2 GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS LIPOXEN TECHNOLOGIES LIMITED (GB) 2011-02-03 WO disclosed
US-20110027350-A1 GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS LIPOXEN TECHNOLOGIES LIMITED (GB) 2011-02-03 US disclosed
US-20110028693-A1 BLOOD COAGULATION PROTEIN CONJUGATES BAXTER INTERNATIONAL INC. (US) 2011-02-03 US disclosed
WO-1996006603-A1 POLYALKYLENE OXIDE CONTAINING QUATERNARY AMMONIUM ANTIMICROBIAL AGENTS ALCON LABORATORIES, INC. (US) 1996-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035344-A1 NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE LPO, OGA, DAO MEN1 4354/4885KMT2A 2819/4885TSHR 3015/4885
US-11564992-B2 Nucleophilic catalysts for oxime linkage LPO, OGA, DAO MEN1 4354/4885KMT2A 2819/4885TSHR 3015/4885
US-20220175939-A1 THERAPEUTIC PROTEINS WITH INCREASED HALF-LIFE AND METHODS OF PREPARING SAME SERPINA6, FCGRT, ALB MEN1 2516/4885KMT2A 4056/4885TSHR 2956/4885
US-20110028693-A1 BLOOD COAGULATION PROTEIN CONJUGATES F13B, F12, F2 MEN1 3815/4885KMT2A 1975/4885TSHR 3460/4885
US-20110027350-A1 GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS HPSE, GYPA, GBA2 MEN1 3778/4885KMT2A 1292/4885TSHR 2965/4885
US-20240335549-A1 THERAPEUTIC PROTEINS WITH INCREASED HALF-LIFE AND METHODS OF PREPARING SAME SERPINA6, FCGRT, ALB MEN1 2516/4885KMT2A 4056/4885TSHR 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.